What does HHV-6 stand for?
Human Herpesvirus 6 (HHV-6) is a set of two closely related herpes viruses known as HHV-6A and HHV-6B. HHV-6B infects nearly 100% of human beings, typically before the age of three and often results in fever, diarrhea, sometimes with a rash known as roseola.
Is HHV-6 an STD?
It is known that children do acquire HHV-6A from family members in Africa. One potential route of transmission could be through the nose. Several studies have suggested that HHV-6A could also be transmitted sexually (Chang 1994, Leach 1994).
Does everyone have HHV-6?
Although nearly everyone is infected with HHV-6 in childhood, only a small percentage experience reactivation of HHV-6 later in life. Moreover, many of these reactivation events never cause symptoms.
What does HHV-6 cause?
Roseola, also called exanthem subitum and sixth disease, is a common, contagious viral infection caused by the human herpesvirus (HHV) 6. This strain of the herpes virus is different than the one that causes cold sores or genital herpes infections. Roseola occurs most often in children aged 6 to 24 months.
What does HHV-6 and HHV‐7 stand for?
“Human Herpesvirus‐6 and ‐7 (HHV‐6 and HHV‐7)”. 25 October 2004. Accessed 5 February 2019. ↩ ↩ ScienceDirect. “Human Herpesvirus 7”. 2012. Accessed 5 February 2019. ↩ ↩
What is herpesvirus 7 (HHV-7)?
Human herpesvirus 7 (HHV-7) was discovered in the peripheral blood lymphocytes of a healthy adult in 1990 [81]. HHV-7 belongs to the Roseolovirus genus within the Betaherpesvirinae subfamily, along with HHV-6 and CMV. Similar to HHV-6, it causes primary infection in most individuals during childhood.
What is the pathophysiology of HHV-7?
HHV-7 is frequently shed in saliva at high levels throughout life in most adults and children. 73 The virus has been detected in breast milk and establishes latency in CD4 + cells. HHV-7 induces degradation of major histocompatibility complex (MHC) class I molecules.
Can HHV6 and HHV-7 be found in CSF?
Investigators have been unable to culture HHV-6 or HHV-7 from cerebrospinal fluid (CSF) ( 14 ). However, HHV-6 and HHV-7 DNA have been detected in CSF and other body fluids by polymerase chain reaction (PCR), which implicates these viruses in neurologic disorders.