Can scleroderma patients get pregnant?
The majority of women with scleroderma will have normal fertility. Young women with scleroderma may have a higher risk of infertility than older women who have had previous children (Lambe et al 2004).
What is SSc in pregnancy?
Systemic sclerosis (SSc) is a CTD that affects women of childbearing age at least five times more than men [1]. For a long time, SSc has been considered a strict contraindication for pregnancy, because patients were thought to be at high risk for poor fetal and maternal outcome, including maternal death [2].
Can scleroderma cause miscarriages?
Scleroderma and fertility Fertility is usually not affected by scleroderma. However, some medications women with the condition may be using, such as cyclophosphamide and methotrexate, can cause infertility or miscarriage.
Are you born with scleroderma?
Anyone can get scleroderma, but it does occur much more often in women than in men. Several combined factors appear to influence the risk of developing scleroderma: Genetics. People who have certain gene variations appear to be more likely to develop scleroderma.
Can scleroderma cause infertility?
Women with scleroderma who become pregnant may be at higher risk of some adverse pregnancy outcomes such as premature births and small-for-gestational-age infants (16). Some evidence also exists that prior to disease onset, scleroderma patients have higher rates of infertility and delays in conception.
Can pregnancy worsen Raynaud’s?
Two percent of patients reported perinatal death. Dr Caldwell Arnold concluded that patients with Raynaud’s phenomenon appear to be at increased risk for vascular complications during pregnancy, such as hypertensive disorders, emergent deliveries, and poor neonatal outcomes.
Does Morphea affect pregnancy?
Thus pregnancy might be a predisposing factor of morphea because of the microchimerism. Indeed, chimeric cells are none self-cells transferred from fetus to mother during pregnancy. In addition, the pregnancy can alter the disease course of autoimmune diseases, including localized scleroderma.
Does Raynaud’s get worse with pregnancy?
CONCLUSION: Patients with Raynaud’s phenomenon appear to be at increased risk for vascular complications during pregnancy such as hypertensive disorders, emergent deliveries, and poor neonatal outcomes. Obstetric providers should be aware of their increased risk and manage pregnancies accordingly.
How many kids have scleroderma?
There are only 5,000 to 7,000 children with scleroderma in the United States. It is more common in adults then children. Only two percent of all people with scleroderma develop the disease before age 10, and seven percent develop it between ages 10 and 19.