What are the differential diagnosis of pancytopenia?

Differential diagnosis of pancytopenia in an adult. An adult differential checklist for Pancytopenia will also take into account Paroxysmal nocturnal hemoglobinuria which may have symptoms of previous venous thrombosis, fatigue, intermittent abdominal pain, dark urine, blood in stool and pancytopenia.

What infections can cause pancytopenia?

If you have pancytopenia, you have a combination of three different blood diseases: anemia, or low level of red blood cells. leukopenia, or low level of white blood cells….viral infections, such as:

• Epstein-Barr virus, which causes mononucleosis.
• cytomegalovirus.
• HIV.
• hepatitis.
• malaria.
• sepsis (a blood infection)

What happens in pancytopenia?

Pancytopenia occurs when a person has a decrease in all three blood cell types. This happens when something is wrong with the bone marrow, where blood cells are formed. Pancytopenia has many possible causes: Diseases such as cancer, lupus or bone marrow disorders.

What is the criteria for pancytopenia?

In pancytopenia, a CBC will show deficient levels of all the types of blood cells including: A red blood cell count of fewer than 4.2 million cells per microliter (ul) in women or less than 4.7 million cells/ul in men (This may also be described by a low hemoglobin level).

What is the major safety factor related to pancytopenia?

Although pancytopenia is unavoidable in many cases, you may be able to lower your risk of pancytopenia by: Avoiding environmental contaminants (for example, benzene or arsenic) Avoiding radiation exposure.

Does pancytopenia include neutropenia?

Pancytopenia may present with the following emergencies: Neutropenia (new diagnosis or associated with fever/infection) Metabolic emergencies (eg, symptomatic hyperkalemia, hypercalcemia, tumor lysis syndrome) Disseminated intravascular coagulation.

Does pancytopenia include thrombocytopenia?

Pancytopenia is a descriptive term referring to the combination of low levels of all of the types of blood cells including red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia).

What is the difference between pancytopenia and thrombocytopenia?

What bacteria causes pancytopenia?

Sepsis, tuberculosis, or fungal infection can cause pancytopenia. HIV infection can also result in pancytopenia from the infection itself, superimposed infections, or medications used to treat the infection.

Is pancytopenia a life threatening disease?

Pancytopenia is serious and should not be ignored. Without treatment, it can lead to life-threatening symptoms that affect the entire body such as oxygen shortage and immune system problems. How common is pancytopenia? Because of its ties to a wide range of illnesses, pancytopenia is a somewhat common blood cell problem.

What are the signs and symptoms of pancytopenia?

Fatigue

What drugs can cause pancytopenia?

What medications can cause pancytopenia? Medications that can affect bone marrow function include chloramphenicol, chemotherapy drugs, thiazide diuretics, anti-epileptic drugs, colchicine, azathioprine, and non-steroidal anti-inflammatory drugs (NSAIDs). The list here covers just some of the potential disease-related pancytopenia causes.

What can cause pancytopenia?

There are many causes of pancytopenia. Any of the following may cause pancytopenia: A genetic condition that causes low blood cell levels An autoimmune condition that attacks the bone marrow Not enough folic acid or vitamin B12 in the foods you eat Exposure to toxins such as benzene, arsenic, or insecticides