What are the different types of thrombocytopenia?
Types of thrombocytopenia
- idiopathic (or immune) thrombocytopenic purpura (ITP)
- thrombotic thrombocytopenic purpura (TTP)
- haemolytic uraemic syndrome (HUS).
What is the most common type of thrombocytopenia?
One of the most common causes of low platelets is a condition called immune thrombocytopenia (ITP). You may hear it called by its old name, idiopathic thrombocytopenic purpura.
What are 3 causes of thrombocytopenia?
Factors that can decrease platelet production include:
- Leukemia and other cancers.
- Some types of anemia.
- Viral infections, such as hepatitis C or HIV.
- Chemotherapy drugs and radiation therapy.
- Heavy alcohol consumption.
What are the four mechanisms of thrombocytopenia?
There are four primary causes of thrombocytopenia: hypoproliferation (lack of production), sequestration, consumption (utilization), and destruction.
What causes secondary thrombocytopenia?
Secondary ITP is known to be caused by systemic autoimmune disorders, primary or secondary immunodeficiency, infectious diseases, paraneoplastic syndromes (e.g., lymphomas and other malignancies), and drug-dependent antibodies (5).
What platelet count is thrombocytopenia?
A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Having more than 450,000 platelets is a condition called thrombocytosis; having less than 150,000 is known as thrombocytopenia.
What are the signs and symptoms of thrombocytopenia?
What are the symptoms of thrombocytopenia?
- Bleeding gums.
- Blood in stool (black, tarry-looking), urine (hematuria) or vomit.
- Heavy menstrual periods.
- Petechiae (tiny red or purple dots on the lower legs that resemble a rash).
- Purpura (purple, red or brown bruises) or bruising easily.
- Rectal bleeding.
Which drugs can cause thrombocytopenia?
Other medicines that cause drug-induced thrombocytopenia include:
- Furosemide.
- Gold, used to treat arthritis.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Penicillin.
- Quinidine.
- Quinine.
- Ranitidine.
- Sulfonamides.
What drugs can cause thrombocytopenia?
Is ITP primary or secondary?
Immune thrombocytopenic purpura (ITP), a condition of low platelets, can occur from primary causes, often referred to as idiopathic thrombocytopenic purpura, or secondary to an underlying disease, such as an autoimmune disorder or an infection.
What is primary and secondary ITP?
ITP is an autoimmune bleeding disorder caused by various etiologies, which is characterized by increased platelet destruction and impaired production, resulting in a decreased platelet count. Primary ITP is idiopathic, whereas secondary ITP is linked to an underlying condition (1).
What drugs cause thrombocytopenia?
Platelet destruction such as with an auto-antibody that attaches to the platelet surface.
What are home remedies for thrombocytopenia?
peanuts
What tests can diagnose thrombocytopenia?
Closure time. This test measures the time it takes for platelets in a blood sample to plug a small hole in a tiny tube.
Which signs and symptoms are classic for thrombocytopenia?
Thrombocytopenia signs and symptoms may include: Easy or excessive bruising (purpura) Superficial bleeding into the skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on the lower legs. Prolonged bleeding from cuts. Bleeding from your gums or nose. Blood in urine or stools.