What is acetazolamide used for?
Acetazolamide is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Acetazolamide decreases the pressure in the eye.
How is acetazolamide administered?
The direct intravenous route of administration is preferred. Intramuscular administration is not recommended. Acetazolamide should be used as an adjunct to the usual therapy.
How do you reconstitute Diamox IV?
Reconstitute with at least 5 mL sterile water to provide a solution containing not more than 100 mg/mL. Store drug product at controlled room temperature 15°-30°C (59°-86°F). Reconstituted solution should be stored in refrigerator at 2°- 8°C (36° – 46°F). Use within 12 hours of reconstitution.
What type of drug is acetazolamide?
Acetazolamide is a diuretic and carbonic anhydrase inhibitor medication that is used to treat several illnesses. FDA-approved indications include glaucoma, idiopathic intracranial hypertension, congestive heart failure, altitude sickness, periodic paralysis, and epilepsy.
Is acetazolamide an antibiotic?
Acetazolamide (Brand Name: Diamox) is a “water pill” (diuretic) used to prevent and reduce the symptoms of altitude sickness. Acetazolamide is also used with other medications to treat a certain type of eye problem (open-angle glaucoma). Acetazolamide is available in generic form.
When should you take acetazolamide?
To prevent altitude sickness, start taking acetazolamide 1 to 2 days before you start to climb. Continue taking it while you are climbing and for at least 48 hours after you have reached your final altitude. You may need to continue taking this medication while staying at the high altitude to control your symptoms.
How do you dilute acetazolamide?
Reconstitute with at least 5 mL sterile water to provide a solution containing not more than 100 mg/mL. Reconstituted solution may be refrigerated (2°C to 8°C) for 1 week, however, use within 12 hours is recommended. Further dilute in D5W or NS for I.V.
Can Diamox be given IV push?
Intravenous or intramuscular injection. The direct intravenous route is preferred as intramuscular use is limited by the alkaline pH of the solution. Hypersensitivity to acetazolamide or to any of the excipients listed in section 6.1. DIAMOX injection should not be used in patients hypersensitive to sulphonamides.
Can acetazolamide be crushed?
Acetazolamide 250mg Tablets should be swallowed whole with a drink of water, just before or just after a meal. Do not chew or crush the tablets.
Who should not use acetazolamide?
Do not take Acetazolamide 250mg Tablets if: you know you are allergic to sulphonamides, sulphonamide derivatives including acetazolamide or to any of the ingredients in the medicine (listed in Section 6) you have severe liver problems. you have or have ever had severe kidney problems.
Does acetazolamide lower blood pressure?
Acetazolamide Reduces Blood Pressure and Sleep-Disordered Breathing in Patients With Hypertension and Obstructive Sleep Apnea: A Randomized Controlled Trial.
Can I crush acetazolamide?
How is acetazolamide prepared for intravenous use?
Acetazolamide is available for intravenous use, and is supplied as a sterile powder requiring reconstitution. Each vial contains acetazolamide sodium equivalent to 500 mg of acetazolamide. The bulk solution is adjusted to pH 9.6 using sodium hydroxide and, if necessary, hydrochloric acid prior to lyophilization.
What are the ingredients in acetazolamide?
Each tablet, for oral administration, contains 250 mg of acetaZOLAMIDE. In addition, each tablet contains the following inactive ingredients: lactose monohydrate, sodium starch glycolate, corn starch, and calcium stearate.
What is acetazolamide extended-release capsules?
Acetazolamide extended-release capsules are an inhibitor of the enzyme carbonic anhydrase. Acetazolamide is a white to faintly yellowish white crystalline, odorless powder, weakly acidic, very slightly soluble in water, and slightly soluble in alcohol.
How many mg of acetazolamide sodium are in a vial?
Each vial contains acetazolamide sodium equivalent to 500 mg of acetazolamide. The bulk solution is adjusted to pH 9.6 using sodium hydroxide and, if necessary, hydrochloric acid prior to lyophilization.