What does Idexx SDMA test for?
Chronic kidney disease is a common condition in dogs and a leading cause of death in cats. The IDEXX SDMA™ Test helps identify disease earlier and is complementary to existing kidney tests. Early identification should prompt investigation for an underlying cause, giving the potential for specific treatment.
How is SDMA tested?
Diagnosing chronic kidney disease in dogs Thousands of veterinarians are now using the SDMA test along with creatinine, BUN and urine specific gravity to check pets for kidney disease.
What does an elevated SDMA mean?
An elevated SDMA* concentration is a reflection of impaired glomerular filtration rate (GFR). Both primary kidney disease and secondary kidney insults, such as concurrent disease, can cause an elevation in SDMA concentration.
What does SDMA mean?
SDMA stands for symmetric dimethylarginine. SDMA is an amino acid produced in the body when protein is broken down and then excreted through the kidneys. It is mea- sured to detect kidney disease. • SDMA is a methylated form of arginine in intracellular proteins of all nucleated cells.
What sample is needed for SDMA?
What’s the sample size I need to run SDMA? The recommended sample volume to run the Catalyst SDMA Test depends on the type of sample you’re using. For whole blood, we recommend 600–800 µL. If you’re testing serum/plasma, we recommend 65 µL, or 300 µL to run SDMA with other tests.
What is blood SDMA?
Symmetric dimethylarginine (SDMA) is a sensitive circulating kidney biomarker whose concentrations increase earlier than creatinine as glomerular filtration rate decreases. Unlike creatinine SDMA is unaffected by lean body mass.
What is SDMA in kidney disease?
Can UTI cause elevated SDMA?
SDMA is a more sensitive indicator of kidney function than creatinine in AKI as well as CKD and increases earlier. In pets like Reese, an increased SDMA in the face of a urinary tract infection should lead to additional investigation and a consideration for more aggressive treatment for pyelonephritis.
How sensitive is SDMA?
IDEXX SDMA is a reliable marker for kidney disease, that is both sensitive and specific, increasing on average when there is a 40% reduction in GFR due to cancer or other conditions.
Is there an SDMA test for humans?
SDMA is the subject of more than 30 ongoing research collaborations. This novel immunoassay for measuring Symmetric Dimethylarginine (SDMA) with comparable performance to LC-MS/MS is now validated for use in humans and is better suited for high-throughput clinical laboratory testing.
Is SDMA affected by UTI?
Discussion. SDMA is a more sensitive indicator of kidney function than creatinine in AKI as well as CKD and increases earlier. In pets like Reese, an increased SDMA in the face of a urinary tract infection should lead to additional investigation and a consideration for more aggressive treatment for pyelonephritis.
When should I run SDMA?
Run SDMA every time you run creatinine and BUN SDMA is more reliable than creatinine as an indicator of kidney function because it is not influenced by confounding conditions. SDMA is an earlier indicator of progressive kidney function loss, often increasing before other parameters.
What is IDEXX SDMA test algorithm?
IDEXX Reference Laboratories includes the IDEXX SDMA Test in all routine chemistry panels. There’s no additional cost and the turnaround time is the same. SDMA is increased. Now what? Use the IDEXX SDMA Test Algorithm to take the appropriate steps towards confirming disease and diagnosis. Need help getting your practice set up with SDMA testing?
How much does it cost to get SDMA from IDEXX?
Get SDMA for $6.99 or less for your Catalyst One or Catalyst Dx chemistry analyzer. The IDEXX SDMA Test is included with every chemistry panel or as a stand-alone test from IDEXX Reference Laboratories. How do I reorder Catalyst SDMA slides? To reorder Catalyst SDMA slides, sign in to your IDEXX Online Orders account.
Is IDEXX SDMA a reliable marker of kidney disease?
IDEXX SDMA is a reliable marker for kidney disease, that is both sensitive and specific, increasing on average when there is a 40% reduction in GFR due to cancer or other conditions. Cancer patients with increased SDMA should be carefully managed since structural kidney disease is often present that results in CKD.
What is IDEXX SDMA in dogs?
SDMA offers another tool for recognition of dogs and cats with early kidney disease. An increased IDEXX SDMA concentration should be investigated, managed, and monitored to determine the probability of kidney disease and whether it is likely due to ongoing kidney injury or part of CKD.
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