What is levofloxacin IV used for?

Levofloxacin injection is used to treat bacterial infections in many different parts of the body. It is also used to prevent an anthrax infection after inhalational exposure. This medicine is also used to treat and prevent plague (including pneumonic and septicemic plague).

Can you give levofloxacin IV?

Levofloxacin Ibigen solution for infusion is administered by slow intravenous infusion once or twice daily. The infusion time must be at least 30 minutes for 250 mg or 60 minutes for 500 mg Levofloxacin Ibigen solution for infusion (see section 4.4).

Why is vancomycin given IV?

However, the drug has poor oral bioavailability and is broken down in the stomach and intestines before it can enter the bloodstream to treat systemic infections. As a result, for systemic infections, vancomycin is given intravenously (IV) for better efficacy.

Is levofloxacin PO or IV?

Less susceptible pathogens may require an increased daily dose for more optimal therapy. Orally administered levofloxacin appears to be well absorbed in selected ICU patients and has pharmacokinetics similar to those of intravenously administered levofloxacin.

Is levofloxacin a strong antibiotic?

Levaquin is a brand-name version of levofloxacin, a strong antibiotic used for treating several different infections, including pneumonia. Levaquin is approved by the Food and Drug Administration (FDA), and is one of a class of antibiotics called fluoroquinolones. These drugs work by killing bacteria in the body.

How often is IV Levaquin given?

The usual dose of LEVAQUIN® Injection is 250 mg or 500 mg administered by slow infusion over 60 minutes every 24 hours or 750 mg administered by slow infusion over 90 minutes every 24 hours, as indicated by infection and described in Table 1.

What are the most common drug interactions with levofloxacin?

Common medications that may interact with levofloxacin include:

• antacids containing magnesium or aluminum.
• blood-glucose-lowering agents, such as insulin or glimepiride.
• corticosteroids, such as prednisone.
• bowel cleansing agents such as sodium picosulfate.
• lactobacillus.
• NSAIDs such as ibuprofen, diclofenac, or naproxen.

How long should you be on vancomycin IV?

Vancomycin shall only be administered as slow intravenous infusion of at least one hour duration or at a maximum rate of 10 mg/min (whichever is longer) which is sufficiently diluted (at least 100 ml per 500 mg or at least 200 ml per 1000 mg) (see section 4.4).

Is vancomycin the strongest antibiotic?

Vancomycin is active only with respect to Gram-positive bacteria. It is the most powerful of all of the known antibiotics with respect to S. aureus and Staphylococcus epidermidus, including methicillin- and cephalosporin-resistant strains.

How often is Levaquin IV given?

What is the most common route of administration for levofloxacin?

Levofloxacin injection should be administered to both adult or pediatric patients by slow intravenous infusion over 60 minutes (for 250 to 500 mg) and over 90 minutes (for 750 mg).

Is levofloxacin stronger than amoxicillin?

The results of this study show that once-daily administration of levofloxacin is as effective and better tolerated than amoxicillin-clavulanate administered 3 times daily for treating acute sinusitis in adult outpatients.