What does pemphigoid look like?

It usually starts as sore, itchy patches. On white skin the patches look red or pink. On brown and black skin they may look dark reddish-brown. It can affect large areas of the body or limbs.

What is difference between pemphigus and pemphigoid?

Pemphigus is characterized by shallow ulcers or fragile blisters that break open quickly. Pemphigoid presents with stronger or “tense” blisters that don’t open easily. Those with pemphigoid are also more likely to have hot, red and itchy hive spots.

Can pemphigoid be fatal?

Bullous pemphigoid is a chronic, inflammatory, subepidermal, blistering disease. If untreated, it can persist for months or years, with periods of spontaneous remissions and exacerbations. The disease can be fatal, particularly in patients who are debilitated.

What triggers pemphigus?

Pemphigus vulgaris is not fully understood. Experts believe that it’s triggered when a person who has a genetic tendency to get this condition comes into contact with an environmental trigger, such as a chemical or a drug. In some cases, pemphigus vulgaris will go away once the trigger is removed.

How do you diagnose pemphigoid?

Pemphigus and pemphigoid are diagnosed through special testing and clinical presentation. Types of testing include: Lesion biopsy — a sample of the blistered skin is removed and examined under the microscope. Additionally, the layer of skin in which cell-to-cell separation occurs can be determined.

What happens if pemphigoid is left untreated?

Infection that spreads to your bloodstream (sepsis) Malnutrition, because painful mouth sores make it difficult to eat. Medication side effects, such as high blood pressure and infection. Death, if certain types of pemphigus are left untreated.

Who gets pemphigus?

Middle-aged or older people are most likely to get pemphigus, including the most common type, pemphigus vulgaris. This type usually begins between 50 and 60 years of age. Your risk of getting pemphigus vulgaris increases if you have: Jewish ancestry, especially Ashkenazi Jewish heritage.