Can anticholinergics cause urinary retention?
Urinary retention has been described with the use of drugs with anticholinergic activity (e.g. antipsychotic drugs, antidepressant agents and anticholinergic respiratory agents), opioids and anaesthetics, alpha-adrenoceptor agonists, benzodiazepines, NSAIDs, detrusor relaxants and calcium channel antagonists.
How do anticholinergics affect urination?
Anticholinergic drugs block the action of a chemical messenger — acetylcholine — that sends signals to your brain that trigger abnormal bladder contractions associated with overactive bladder. These bladder contractions can make you feel the need to urinate even when your bladder isn’t full.
What medication can cause urinary retention?
Urinary stones can also block the flow of urine out of your body. Urinary retention can also be caused by certain medications. Drugs like antihistamines (Benadryl®), antispasmodics (like Detrol®), opiates (like Vicodin®) and tricyclic antidepressants (like Elavil®) can change the way the bladder muscle works.
Do anticholinergics cause urinary incontinence?
The drugs commonly pinpointed in urinary incontinence include anticholinergics, alpha-adrenergic agonists, alpha-antagonists, diuretics, calcium channel blockers, sedative-hypnotics, ACE inhibitors, and antiparkinsonian medications.
What causes urinary retention?
The causes of urinary retention are related to either a blockage that partially or fully prevents urine from leaving your bladder or urethra, or your bladder not being able to maintain a strong enough force to expel all the urine.
Can drugs affect your bladder?
The bladder is vulnerable to the adverse effects of drugs because of its complex control and the frequent excretion of drug metabolites in the urine. Incontinence results when bladder pressure exceeds sphincter resistance.
What is the most common cause of urinary retention?
Why are anticholinergic drugs bad?
“(Anticholinergic drugs) can cause a range of side effects such as constipation, difficulty with bladder control,” she said. “They can cause acute changes in cognition, meaning slight changes in cognition, and delirium. More recently, there is mounting evidence that they might be linked to dementia.”
How long does anticholinergic side effects last?
In the case of overdose, atropine and scopolamine cause anticholinergic syndrome. The anticholinergic toxicity usually occurs within 30–60 min after consumption of the plant, and the symptoms can last for 24–28 h due to delayed gastric emptying caused by the anticholinergic alkaloids.
What drugs can cause urinary incontinence?
Pharmacologic agents including oral estrogens, alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, nonsteroidal anti-inflammatory drugs, and calcium channel blockers have been implicated to some degree in the onset or exacerbation of urinary incontinence.
What medicines cause urinary retention?
– Uher R, Rarmer A, Henigsberg N, et al. Adverse reactions to antidepressants. – Verhamme K, Miriam C, Sturkenboom M, et al. – Asimakopoulos AD, De Nunzio C, et al. – Sakakirbara R, Hattori T, et al. – Choong S, Emberton M. – James R, Frasure HE, Mahaja ST. – Rosow CE, Gomery P, Chen TY, et al. – Garten L, Buhrer C. – Lenze EJ.
Which medication causes urine retention?
Symptoms. Urinary retention is not a disease but a symptom related to health problems directly or indirectly affecting the urinary tract.
Why do antidepressants cause urinary retention?
Tsakiris P,Oelke M,Michel MC. Drug-induced urinary incontinence.
What are the signs of urinary retention?
– age-related loss of bladder muscle strength – overdistention—a bladder that has been stretched such that the muscles are damaged – pregnancy and childbirth – trauma