Can Stage 4 metastatic lung cancer go into remission?
Complete remission of advanced NSCLC can be achieved using the combination of oral icotinib and BAI chemotherapy. Core tip: Few patients can undergo surgery for treatment of non-small-cell lung cancer because of advanced disease or poor pulmonary function.
What is the prognosis for lung cancer that has metastasized?
When cancer has spread to distant parts of the body, called metastatic lung cancer, the 5-year survival rate is 7%. It is important to note that newer therapies like targeted treatments and immunotherapies (see Types of Treatment) are allowing people with metastatic lung cancer to live longer than ever before.
What is first line treatment for metastatic lung cancer?
Platinum doublet chemotherapy has historically been the standard first-line therapy for patients who are diagnosed with metastatic lung adenocarcinoma without a targetable mutation.
How is metastatic lung cancer treated?
Most people with the disease can have treatment with a mix of radiation, chemotherapy, and targeted therapies — drugs that attack specific parts of the cancer cells. Your doctor will recommend the therapies they think are most likely to help you.
How is cisplatin + pemetrexed used to treat lung cancer?
Cisplatin + pemetrexed can be given either after surgery to eliminate microscopic cells, or cisplatin + pemetrexed can be given before surgery to shrink the size of the tumor and minimize the size of the lung surgery.
What is the prognosis of vinorelbine and pemetrexed plus cisplatin?
At a median follow-up of 45.2 months, median recurrence-free survival was 37.3 months for vinorelbine plus cisplatin and 38.9 months for pemetrexed plus cisplatin, with a hazard ratio of 0.98 (95% CI, 0.81 to 1.20; 1-sided P= .474).
Is pemetrexed plus cisplatin better for resected nonsquamous NSCLC?
Although this study failed to show the superiority of pemetrexed plus cisplatin for patients with resected nonsquamous NSCLC, this regimen showed a better tolerability as adjuvant chemotherapy.
What is the toxicity of vinorelbine plus cisplatin?
Grade 3-4 toxicities reported more frequently for vinorelbine plus cisplatin than for pemetrexed plus cisplatin were febrile neutropenia (11.6% v0.3%, respectively), neutropenia (81.1% v22.7%, respectively), and anemia (9.3% v2.8%, respectively). One treatment-related death occurred in each arm.
