How do you administer GONAL-f injection?
Place the outer needle cap on a flat surface. Hold the GONAL-f ® Pen firmly with one hand, and slip the needle into the outer needle cap. Be careful not to prick yourself with the needle. Continue by pushing the capped needle against a firm surface until you hear a “click.”
Does it matter where you inject GONAL-f?
GONAL-f is usually given in the lower abdominal area (except around the navel and waistline) or the front of your thigh. The injection site should be changed daily to lessen possible injection site reactions. Do not inject into any areas in which you feel lumps, firm knots, depressions, pain, or see any discolouration.
What time should I inject GONAL-f?
GONAL-f is usually given every day. cycle. If you do not have periods you can start using the medicine on any convenient day. The usual starting dose of GONAL-f is 75 to 150 IU each day.
Is GONAL-f injection painful?
In women, Gonal-f (follitropin alfa) can cause OHSS, a condition that occurs when the ovaries grow too large after you have finished your injections. It is very painful and can cause vomiting and diarrhea. It can also cause more serious conditions, including touble breathing and bursting ovaries.
How fast do follicles grow on GONAL-f?
2 mm per day
As medication is introduced, the follicles will begin to grow, roughly an average of 2 mm per day during the later stages of stimulation.
Does GONAL-f need to be room temperature before injection?
Instruct women to remove the Gonal-f® RFF Redi-ject® from the refrigerator at least 30 minutes prior to use in order to allow Gonal-f® RFF Redi-ject® to warm to room temperature and avoid the discomfort of a cold injection.
How fast do follicles grow on Gonal F?
How do you know if Gonal F is working?
The only way to know whether Gonal F is working is to monitor with blood tests and ultrasound.
How do you know Gonal F is working?
Can follicles grow in 2 days?
Timmreck. “Early on, follicular growth may be minimal, but once the follicle(s) have committed to ‘active’ growth, then they may grow 1-3 mm per day.” The number of follicles produced is also dependent on the treatment option.
How many eggs are in one follicle?
one egg
How may eggs will there be in a follicle? In a normal menstrual cycle one follicle will grow containing one egg. The follicle will get bigger until it ruptures at ovulation which then releases the egg.
How does Gonal make you feel?
A concise overview of the drug for the patient or caregiver from First DataBank. SIDE EFFECTS: Headache, nausea, vomiting, mild stomach/abdominal pain, bloating, redness/pain at the injection site, or breast tenderness/pain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What is Gonal-F injection?
Gonal-f injection is a fertility drug that contains gonadotropins, which are used for ovarian stimulation cycles in fertility treatment cycles, like IVF.Dosages available range from 75 IU to 1050 IU, although the most common are Gonal-f 300, Gonal-f 450, and Gonal-f 900.
What is the pharmacokinetics of Gonal-F®?
Steady state pharmacokinetics were also determined in 6 healthy adult male volunteers who were administered a single daily dose of 225 IU Gonal-f®for 7 days. No significant difference in pharmacokinetics is expected in males versus females when administered Gonal-f®subcutaneously.
What happens when you take Gonal-F?
Pharmacodynamics Following daily subcutaneous administration of 150 IU of Gonal-f®for 7 days in healthy female volunteers, serum inhibin and estradiol, and total follicular volume responded as a function of time, with pronounced inter-individual variability. Pharmacodynamic effect lagged behind FSH serum concentration.
What are the ingredients in Gonal-F?
Multiple Dose vials are reconstituted with Bacteriostatic Water for Injection (0.9% benzyl alcohol), USP. Under current storage conditions, Gonal-fmay contain up to 10% of oxidized follitropin alfa.