How is sunitinib malate administered?
The recommended dosage of SUTENT for the adjuvant treatment of RCC is 50 mg taken orally once daily, on a schedule of 4 weeks on treatment followed by 2 weeks off (Schedule 4/2), for nine 6-week cycles. SUTENT may be taken with or without food.
What is sunitinib used for?
Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with imatinib (Gleevec) or people who cannot take imatinib.
How long can you take sunitinib?
If you have kidney cancer or a GIST, you usually take sunitinib once a day for 4 weeks, followed by 2 weeks without the drug (rest period). This makes up a cycle of treatment that lasts for 6 weeks.
What is the best way to take sunitinib?
Here are a few things you should know about taking SUTENT:
- Take SUTENT exactly the way your healthcare provider tells you.
- Take SUTENT 1 time each day with or without food.
- Do not open the SUTENT capsules.
- Do not drink grapefruit juice or eat grapefruit during your treatment with SUTENT.
- Do not take St.
When should we take sunitinib?
You usually take sunitinib once a day for 4 weeks. You then have a 2 week break, when you don’t take the capsules. This 6 week period is called a cycle of treatment. After 6 weeks, you start a new cycle of treatment.
Is sunitinib an immunotherapy?
Their primary options were two types of immunotherapy drugs, interferon-alpha and interleukin-2, then the targeted therapy sunitinib (Sutent®), which was approved in 2006. Since then, sunitinib has remained the standard of care as initial treatment for this disease.
What is the best time to take sunitinib?
Sunitinib comes as a capsule to take by mouth with or without food. Do not open the capsules. Your dose and schedule is determined by your healthcare provider and is based on the type of cancer you have. Take sunitinib at around the same time every day.
How do you take sunitinib?
Is axitinib a targeted therapy?
Axitinib is a targeted therapy that targets and binds to the vascular endothelial growth factor receptors (VEGFR) on the inside of cancer cells.
What is sunitinib malate used to treat?
FDA label information for this drug is available at DailyMed. Sunitinib malate is approved to treat: Gastrointestinal stromal tumor (a type of stomach cancer ). It is used in patients whose condition has become worse while taking imatinib mesylate or who are not able to take it. Pancreatic cancer.
Does sunitinib work against pancreatic neuroendocrine tumors?
Background: The multitargeted tyrosine kinase inhibitor sunitinib has shown activity against pancreatic neuroendocrine tumors in preclinical models and phase 1 and 2 trials.
What is the duration of Sunitinib treatment?
Study Treatment. Patients received sunitinib for a median duration of 4.6 months (range, 0.4 to 17.5), and patients received placebo for a median duration of 3.7 months (range, 0.03 to 20.2).
Does sunitinib cause death?
The deaths were attributed to the disease under study, with the exception of grade 5 cardiac failure (in one patient who received sunitinib) and grade 5 dehydration (in one patient who received placebo), which were both considered to be related to the study drug.