Is Andrographis good for cancer?

In recent years, increased number of studies have revealed that andrographis treatment leads to inhibition in cell proliferation and high rates of apoptosis in a variety of human cancer cells.

Is Andrographis paniculata toxic?

Although the standardized extract of A. paniculata, containing high AP content, was reported to have no toxicity [9], there is currently no toxicological data available for A.

Can Andrographis be taken long term?

When taken by mouth: Andrographis is likely safe when used in doses up to 340 mg daily for up to 12 months. It also appears to be safe when taken as a specific combination product containing andrographis extract and eleuthero (Kan Jang, Swedish Herbal Institute) for 4-7 days.

What are the health benefits of Andrographis paniculata?

Andrographis has been mostly studied for colds, flu, and upper respiratory infections. Andrographis paniculata is used in traditional medicine to treat infectious diseases and fevers. In the lab, it exhibits antibacterial, antioxidant, anti-inflammatory, anticancer, and immunostimulating properties.

Is andrographis good for the liver?

Although numerous herbal plants have been reported for their efficacies in liver protection, Andrographis paniculata is the most widely used herb for hepatoprotection, particularly in Ayurveda and traditional Chinese medicine.

Is andrographis a blood thinner?

Bleeding conditions: Andrographis might slow blood clotting. This might increase the risk of bleeding or bruising in people with bleeding disorders. Low blood pressure: Research suggests that andrographis might lower blood pressure. This has not been seen in humans.

Is andrographis good for inflammation?

As andrographolide is the major bioactive substance and has a critical effect on inhibiting the release of an important proinflammatory factor TNF-α in APN [43], it may also contribute importantly to suppressing the inflammatory response in this study.

Is andrographis good for the kidneys?

Conclusions: Acute kidney injury may occur shortly after intravenous infusion of andrographolide, with symptoms including flank pain, decreased urine output, and nausea or vomiting. The pathological change might be acute tubular necrosis.

Is andrographis good for the heart?

The dichloromethane (DCM) extract of Andrographis paniculata Nees was tested for cardiovascular activity. The extract significantly reduced coronary perfusion pressure by up to 2 4 . 5 ± 3 . 0 mm Hg at a 3 mg dose and also reduced heart rate by up to 4 9 .

Is andrographis an antibiotic?

Andrographolide (AG), the main active component of the herb Andrographis paniculata, has been used for many years for anti-inflammatory and antibacterial infections.

Is Andrographis paniculata good for the kidneys?

This study strongly suggests that aqueous extract of A. paniculata exhibits a protective action on gentamicin-induced acute renal failure.

Can Andrographis paniculata be used as a methanolic extract for cancer treatment?

Andrographis paniculata extract is traditionally used as a medicine to treat different diseases in India, China and Southeast Asia. In the present study, we evaluated the anticancer and immunomodulatory activity of the methanolic extract of Andrographis paniculata in human cancer and immune cells.

Where can I find chemical components of Andrographis paniculata?

1 Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, China. To investigate the chemical constituents of the roots of Andrographis paniculata, 28 compounds were isolated and identified from the 80% ethanol extract.

Does Andrographis paniculata extract sha-10 reduce the symptoms of common cold?

Use of visual analogue scale measurements (VAS) to asses the effectiveness of standardized Andrographis paniculataextract SHA-10 in reducing the symptoms of common cold. A randomized double blind-placebo study.

Can Andrographis paniculata be taken during pregnancy?

Oral administration of Andrographis paniculata extract during the first 19 days of pregnancy in doses of 200, 600, and 2000 mg/kg did not exhibit any effect on the elevated level of progesterone in the blood plasma of rats [46].