Is apolipoprotein A the same as lipoprotein A?
Lipoprotein(a) [Lp(a)] is a cholesteryl ester–rich lipoprotein distinguished from other lipoproteins by the presence of a unique apolipoprotein (apo), apo(a). Plasma concentrations of Lp(a) vary over a 1000-fold range, and the distribution of levels is highly skewed, with most whites and Asians having low levels.
Is A1 High apolipoprotein good?
High levels of apo A-I is considered protective and can be independent of HDL levels. There are some genetic disorders that lead to deficiencies in apo A-I (and therefore to low levels of HDL).
What happens when lipoprotein is high?
High levels of Lp(a) can create plaque in your blood vessels. This is a buildup of cholesterol that lessens blood flow through your arteries. A high level of Lp(a) can be a sign of cholesterol-related disease, such as coronary artery disease. Research has found it to be an independent risk factor for heart disease.
What causes lipoprotein A to be high?
Besides genetics, Lipoprotein (a) levels may result from increased intake of some types of fats, and some medical conditions. Treatment of elevated Lipoprotein (a) is based on a person’s risk of heart attack or stroke.
How common is high lipoprotein A?
About 1 in 4 people in the population are believed to have elevated blood levels of Lipoprotein (a). African Americans may have higher levels. Besides genetics, Lipoprotein (a) levels may result from increased intake of some types of fats, and some medical conditions.
What is lipoprotein (a) and how do you check it?
A doctor can carry out a blood test to check a person’s Lp (a) levels if they suspect that they may be high. In this article, we look at what determines Lp (a) levels, what different test results might mean, and what steps a person can take to reduce their risk of cardiovascular disease. What is lipoprotein (a)?
What is lipoprotein (a) (LP)?
You may have heard about Lipoprotein (a), Lp (a) or often referred to as “Lp little a.” Lp (a) is an independent risk factor for cardiovascular disease.The level of Lp (a) found in a person’s blood is entirely genetically predetermined. This means that unlike other cardiac risk factors, Lp (a) can’t be modified by diet or exercise.
What is apolipoprotein (A)?
Lipoprotein (a) was discovered in 1963 by Kåre Berg. The human gene encoding apolipoprotein (a) was successfully cloned in 1987. Lipoprotein (a) [Lp (a)] consists of an LDL -like particle and the specific apolipoprotein (a), which is bound covalently to the apoB contained in the outer shell of the particle.
What is the normal range of lipoprotein a?
Some research indicates that a reduction of Lp (a) levels to below 50 mg/dl is desirable, although levels above 25–30 mg/dl may still increase the risk of cardiovascular disease. For example, studies have shown that adults have an increased risk of heart attack and coronary heart disease if they have Lp (a) levels above 30 mg/dl.