Is epichlorohydrin hazardous?
Acute (short-term) inhalation exposure to epichlorohydrin in the workplace has caused irritation to the eyes, respiratory tract, and skin of workers. At high levels of exposure, nausea, vomiting, cough, labored breathing, inflammation of the lung, pulmonary edema, and renal lesions may be observed in humans.
How do you handle epichlorohydrin?
Control measures include: (1) enclosing chemical processes for severely irritating and corrosive chemicals, (2) using local exhaust ventilation for chemicals that may be harmful with a single exposure, and (3) using general ventilation to control exposures to skin and eye irritants.
What is epichlorohydrin used for?
Epichlorohydrin (ECH) is an intermediate chemical used in the production of epoxy resins (about 90% of the total global market), synthetic glycerin, epichlorohydrin elastomers, specialty water treatment chemicals, wetstrength resins for paper production, and surfactants.
What is the signal word for epichlorohydrin?
Epichlorohydrin
| Names | |
|---|---|
| GHS labelling: | |
| Pictograms | |
| Signal word | Danger |
| Hazard statements | H226 , H301 , H311 , H314 , H317 , H331 , H350 |
Is epichlorohydrin a chemical?
Epichlorohydrin (ECH) is another versatile chemical intermediate used in a variety of applications, including epoxy resins, textiles, paper products, inks, dyes, automotive and aircraft parts, biocides, personal care products, and ion-exchange resins.
Does epichlorohydrin react with water?
Epichlorohydrin liquid will produce moderate irritation with corneal injury, while solutions of epichlorohydrin may cause more irritation and injury if the solvent carrying the epichlorohydrin is miscible with water. Epichlorohydrin vapor is also very irritating to the eyes.
What is ECH in chemistry?
Epichlorohydrin (1-chloro-2,3-epoxypropane; ECH) is a clear, colorless liquid with a sweet, pungent odor mostly used to make epoxy resins, also used in water treatment, paper chemicals, synthetic rubbers, and surfactants.
How do you make epichlorohydrin?
At commercial scale, epichlorohydrin is mainly produced via chlorohydrination of allyl chloride, obtained in turn from the chlorination of propylene at high-temperature. Epichlorohydrin is mainly used in the production of bisphenol A, a raw material for epoxy resins, glycerol, and elastomers.
What is epichlorohydrin made from?
What is the pH of epichlorohydrin?
7
Epichlorohydrin, which is colourless and poorly soluble in water and has a pungent, chloroform-like odour, is converted to 3-chloro-1,2-propanediol (α-chlorohydrin) in an aqueous milieu at a pH of 7 and 20°C.
What is the OSHA standard for epichlorohydrin exposure?
The current Department of Labor, Occupational Safety and Health Administration (OSHA) standard for occupational exposure to epichlorohydrin is 5 ppm (19 mg/cu m) as an 8-hour time-weighted average. 1 Studies of carcinogenicity were not available when this standard was developed.
What are the side effects of epichlorohydrin?
Epichlorohydrin. irritation eyes, skin with deep pain; nausea, vomiting; abdominal pain; resp distress, cough; cyanosis; reproductive effects; [potential occupational carcinogen]
Are macrocyclic trichothecenes a risk factor for mold exposure?
Macrocyclic trichothecenes, mycotoxins produced by Stachybotrys chartarum, have been implicated in adverse reactions in individuals exposed to mold-contaminated environments. Cellular and humoral immune responses and the presence of trichothecenes were evaluated in patients with mold-related health complaints.
What is the pathophysiology of immunological dysfunction caused by mold exposure?
Immunological dysfunction has been proposed by those who have demonstrated immunological changes in patients after mold exposure. These changes include elevations of IgG, IgM, IgA, and IgE in addition to increased CD3, CD4, CD8, CD20, and decreased CD56.