What are the indications for neuromuscular blockers?
Neuromuscular blocking agents (NMBAs) are used in clinical practice for conditions requiring paralysis such as rapid sequence intubation (RSI), acute respiratory distress syndrome (ARDS), and general anesthesia.
Is succinylcholine contraindicated in pregnancy?
Thus succinylcholine is an ideal neuromuscular blocker in pregnant females because it provides an excellent intubation conditions along with a short duration of apnea, although it has been observed that the duration of action of succinylcholine is significantly longer in pregnant women as compared with nonpregnant …
Is rocuronium contraindicated in pregnancy?
Rocuronium and the steroidal non-depolarizing muscle relaxant like vecuronium is mostly excreted with bile by hepatic metabolism and classified as the FDA pregnancy category B, and is widely used in general anesthesia of pregnant women.
What will happen and why if succinylcholine given to person during pregnancy?
Succinylcholine Pregnancy Warnings -Plasma pseudocholinesterase levels are decreased in pregnancy and several days postpartum by approximately 25%; therefore, most patients may be expected to show prolonged apnea. -This drug crosses the placenta, but only in small amounts.
Which of the following is a neuromuscular blocking agent?
There are two broad classes of neuromuscular blocking drugs: non-depolarizing agents, of which the prototype is curare (for example, d-tubocurarine, atracurium, metocurine, mivacurium, pancuronium, rocuronium, vecuronium) and depolarizing blockers, such as suxamethonium.
Is Propofol contraindicated in pregnancy?
Propofol Pregnancy Warnings This drug should be used during pregnancy only if the benefit outweighs the risk; some manufacturers consider this drug to be contraindicated in pregnancy. US FDA pregnancy category: Not assigned.
Is sevoflurane contraindicated in pregnancy?
US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed.
Is Propofol safe for pregnancy?
Is atropine safe in pregnancy?
Atropine ophthalmic Pregnancy Warnings US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Is propofol a neuromuscular blocking agent?
Propofol is a widely used drug in anesthesia practice, and its pharmacological characteristics are well known. However, propofol is not known for neuromuscular effects.