What is a succinate buffer?
Succinate buffer is prepared by dissolving succinic acid in distilled water. The pH of the buffer is adjusted with 0.2N sodium hydroxide. Technical Information: pK1 (25°C): 4.21 (useful pH range: 3.2-5.2) pK2 (25°C): 5.64 (useful pH range: 5.5-6.5)
Is succinic acid a buffer?
Mixtures of succinic acid and borax solu- tions furnish buffers over a range of pH from 3.0 to 5.8, while mixtures of primary phosphate and borax give buffers over a range of pH from 6.0 to 9.2.
What is the formula of sodium succinate?
Disodium succinate
| PubChem CID | 9020 |
|---|---|
| Structure | Find Similar Structures |
| Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C4H4Na2O4 |
| Synonyms | Disodium succinate SODIUM SUCCINATE 150-90-3 Disodium butanedioate Succinic acid disodium salt More… |
Is succinate the same as succinic acid?
Succinic acid is a white, odorless solid with a highly acidic taste. In an aqueous solution, succinic acid readily ionizes to form its conjugate base, succinate (/ˈsʌksɪneɪt/). As a diprotic acid, succinic acid undergoes two successive deprotonation reactions: (CH2)2(CO2H)2 → (CH2)2(CO2H)(CO2)− + H.
What is borate buffer used for?
Borate buffered saline (abbreviated BBS) is a buffer used in some biochemical techniques to maintain the pH within a relatively narrow range. Borate buffers have an alkaline buffering capacity in the 8–10 range.
What is citrate buffer used for?
Citrate buffers can be used for RNA isolation, due to its ability to prevent base hydrolysis. The buffer is also used for antigen detection by breaking cross-links between antigens and any substances in its fixation medium.
Is succinic acid volatile?
Synopsis. Succinic acid efficiently retains volatiles for a prolonged time if formulated at high supersaturations where small crystallites are formed.
What is succinic acid used for?
It is a common organic acid, which can be used in many food, chemical, and pharmaceutical industries as a precursor to generate many chemicals such as solvents, perfumes, lacquers, plasticizer, dyes, and photographic chemicals. Succinic acid is also used as an antibiotic and curative agent.
How is disodium succinate made?
How is Disodium Succinate Made? Disodium succinate is synthesized between the reaction of succinic acid and sodium carbonate or sodium hydroxide.
What is succinate formula?
C4H6O4Succinic acid / Formula
What is succinate good for?
Succinate or succinic acid is involved in several chemical processes in the body. In supplements, it is used for symptoms related to menopause such as hot flashes and irritability. Succinate is also applied to the skin for arthritis and joint pain.
What is succinate (succinic acid)?
Succinate (succinic acid) is a citric acid cycle intermediate and functions in the transport of electrons to the mitochondrial electron transport chain. It also functions in innate immune signaling and induces IL-1β production during inflammation.
What is succinate 2-?
Succinate. Succinate(2-) is a dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxy groups of succinic acid. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It is a C4-dicarboxylate, a dicarboxylic acid dianion and a succinate. It is a conjugate base of a succinate(1-).
What is succinate colorimetric assay?
The Succinate Colorimetric Assay Kit is a highly sensitive assay for determining succinate levels (ranging from 2-10 nmole/well) in a variety of samples. Succinate concentration is determined by a coupled enzyme reaction, which results in a colorimetric (450 nm) product proportional to the succinate present.
What is succinate used to measure?
Succinates have been often used for the treatment of hypertension. Succinate measurements can be useful for studying its metabolic, immunological, and therapeutic activities. Succinate Colorimetric Assay Kit has been used to measure the concentration of succinate.
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