What is Intervillous blood flow?
Exchange of oxygen and nutrients take place as the maternal blood flows around terminal villi in the intervillous space. The in-flowing maternal arterial blood pushes deoxygenated blood into the endometrial and then uterine veins back to the maternal circulation.
What is the intervillous space in the placenta?
The intervillous space is simply the space between the mother’s blood vessels and the fetal chorionic villi. It is filled with a pool of maternal blood where bathe the villi. This is where all nutrient, gas and waste exchange occur.
What is the type of blood present in the chorionic villi in the intervillous space?
Evaluation of the Placenta The intervillous space is normally filled with maternal blood and a small amount of fibrin, with the villi evenly spaced; neighboring villi usually do not touch one another.
How is the intervillous space formed?
With this physiologic destructive process, the maternal blood vessels of the endometrium are opened, with the result that the spaces in the trophoblastic network are filled with maternal blood; these spaces communicate freely with one another and become greatly distended and form the intervillous space from which the …
What is the function of the ductus arteriosus in the fetal heart?
The ductus arteriosus is a normal fetal artery connecting the main body artery (aorta) and the main lung artery (pulmonary artery). The ductus allows blood to detour away from the lungs before birth. Every baby is born with a ductus arteriosus.
Does blood enter the intervillous space at the peak of a contraction?
Maternal arteries and veins directly enter the intervillous space after 8 weeks gestation, and the intervillous space will contain about a unit of blood (400–500 mL)….
| Intervillous space | |
|---|---|
| Secondary chorionic villi. Diagrammatic. | |
| Details | |
| Days | 24 |
| Identifiers |
What passes through the primitive umbilical ring?
By the end of the 5th week the primitive umbilical ring contains 1) a connecting stalk within which passes the allantois (primitive excretory duct), two umbilical arteries and one vein; 2) the vitelline duct (yolk sac stalk); and 3) a canal which connects the intra- and extraembryonic coelomic cavities (Figure 2C).
What is the role of the trophoblast?
Trophoblasts are cells that form the outer layer of a blastocyst, which provides nutrients to the embryo, and then develop into a large part of the placenta. Trophoblast invasion is a critical process in the establishment of a successful pregnancy.
What is the function of cytotrophoblast?
The primary function of an interstitial cytotrophoblast is to anchor the growing fetus to the maternal uterine tissue. These cells may invade the whole endometrium and the proximal third of the myometrium.
Are trophoblast cells totipotent?
After the first differentiation, the cells in the human embryo lose their totipotency and are no longer totipotent stem cells because they cannot form a trophoblast. They are now pluripotent stem cells….
| Trophoblast | |
|---|---|
| MeSH | D014327 |
| TE | E6.0.1.1.2.0.2 |
| FMA | 83029 |
| Anatomical terminology |
What is the function of the intervillous space?
The intervillous space has free communication with venous sinusoids at its periphery, and from the 8th week of gestation direct channels can also be observed through the cytotrophoblast shell connecting the maternal spiral arteries with the intervillous space.
How do endovascular trophoblasts invade the spiral arteries?
These extravillous trophoblasts invade the maternal decidua and distal ends of the spiral arteries. Via complex interactions likely involving maternal decidua, glands, and immune cells, the interstitial trophoblasts migrate toward the spiral arteries, invade the arteries, and become endovascular trophoblasts.
What is the intervillous space of the uterus normally filled with?
The intervillous space is normally filled with maternal blood and a small amount of fibrin, with the villi evenly spaced; neighboring villi usually do not touch one another.