What is recanalization?

What is recanalization?

Recanalization is the reestablishment of blood flow into a formerly occluded region (Hall et al., 1989). This phenomenon destabilizes the occluded region and may lead to significant rebleeding at the treatment site.

What is recanalization therapy?

The primary aim of thrombolysis in acute ischemic stroke is recanalization of an occluded intracranial artery. Recanalization is an important predictor of stroke outcome as timely restoration of regional cerebral perfusion helps salvage threatened ischemic tissue.

What is spontaneous recanalization?

Background Spontaneous recanalization is an understudied phenomenon in stroke. It is often overestimated by nonocclusion rates. The heterogeneity of the causes and manifestations of stroke and of the studies assessing vascular patency has created difficulties in assigning accurate rates of its incidence.

What is recanalization of the vas deferens?

Recanalization occurs when epithelial microtubules proliferate through the granulomatous tissue between the severed ends of the vas deferens producing a fistula that allows sperm to pass through [10].

What is recanalization therapy stroke?

Thrombolytic stroke therapy is based on the “recanalization hypothesis,” ie, that reopening of occluded vessels improves clinical outcome in acute ischemic stroke through regional reperfusion and salvage of threatened tissues.

How common is recanalization after vasectomy?

Early failure or recanalization of the vas deferens after vasectomy occurs in approximately 0.3% to 0.6% of cases. 5 This failure occurs when a substantial number of spermatozoa or any motile spermatozoa are identified at least 4 months after vasectomy.

What causes recanalization?

What is organization and recanalization?

Organization and recanalization involves the ingrowth of smooth muscle cells, fibroblasts and endothelium into the fibrin-rich thrombus.

recanalization [re-kan″ә-lĭ-za´shun] formation of new canalsor paths, especially blood vessels, through an obstruction such as a clot; called also canalization. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved. re·ca·nal·i·za·tion

What is recanalization Grade 3?

Recanalization degrees were defined using a cerebral infarction grading system, the thrombolysis in cerebral infarction (TICI) scale; grade 0 = no recanalization, grade 1 and 2a = partial recanalization, and grade 2b and 3 = fully recanalization.

What is recanalization of a thrombus?

1. Restoration of a lumen in a blood vessel following thrombotic occlusion, by organization of the thrombus with formation of new channels. 2. Spontaneous restoration of the continuity of the lumen of any occluded duct or tube, as with postvasectomy recanalization. recanalization.

Does recanalization correlate with clinical recovery after stroke?

In human stroke, complete recanalization correlates with clinical recovery, as predicted from animal models. Recanalization, however, is a process that often begins many minutes before restoration of cerebral blood flow (CBF), because t-PA binding and activity on the clot surface are proportional to the area exposed to blood flow.