What is the process of dengue?
The dengue virus attaches to the surface of a host cell and enters the cell by a process called endocytosis. Once deep inside the cell, the virus fuses with the endosomal membrane and is released into the cytoplasm. The virus particle comes apart, releasing the viral genome.
What is the structure of dengue virus?
The dengue virus has a roughly spherical structure. It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell, the dengue virus hijacks the host cell’s machinery to replicate the viral RNA genome and viral proteins.
What is the shape of poliovirus?
The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus.
What is the pathophysiology of dengue?
Pathophysiology for Dengue. The body responds by producing physiologic changes aimed at elevating body temperature. Modifiable factor: • ENVIRONMENT – the patient lives in a nearby river. The body responds by producing physiologic changes aimed at elevating body temperature.
What are the three phases of dengue fever?
The three phases of dengue include febrile, critical, and recovery. During the febrile phase, a sudden high-grade fever of approximately 40 C occurs that usually lasts two to seven days. Associated symptoms include facial flushing, skin erythema, myalgias, arthralgias, headache, sore throat, conjunctival injection, anorexia, nausea, and vomiting.
What is dengue hemorrhagic fever?
Dengue is the most common and important mosquito-borne viral infection and can manifest as Dengue Fever (DF), which is often a self-limiting febrile illness or less commonly dengue hemorrhagic fever (DHF).
What is the mortality and morbidity of dengue?
A fraction of infections (0.5% – 5%) progress to severe dengue. Without proper treatment, fatality rates may exceed 20%. These occur primarily in children. The typical incubation period for the disease is 4 to 7 days, but it can last from 3 to 10 days.