Who should not use atropine eye drops?
Do not use Atropine Eye Drops if: you are allergic to atropine sulfate or to any of the other ingredients of this medicine (listed in section 6). you suffer from increased pressure in the eye (closed angle or narrow angle glaucoma).
What are the toxic effect of the atropine?
Symptoms. Manifestations of atropine overdose are dose-related and include flushing, dry skin and mucous membranes, tachycardia, widely dilated pupils that are poorly responsive to light, blurred vision, and fever (which can sometimes be dangerously elevated).
Are atropine eye drops safe for children?
Our study discovered that atropine, 0.01%, can slow the progression of myopia and axial length in children with low and moderate myopia, compared with placebo treatment. A once-nightly dose of atropine, 0.01%, eyedrops was well tolerated without serious adverse events.
Can atropine eye drops cause high blood pressure?
Fraunfelder and Scafidi found that concomitant use of phenylephrine eye drops and atropine eye drops can cause blood pressure elevation and induce tachycardia in some patients (Fraunfelder and Scafidi, 1978).
Can atropine eye drops be used long term?
Conclusion: The results of this study demonstrate that long-term and regular instillation of LC atropine eye drops is effective for controlling myopia progression and provides a possible strategy for an initial myopia regimen.
What are atropine drops?
Atropine sulfate eye drops is used to dilate the pupil before eye exams. It is also used to treat an eye condition called amblyopia (lazy eyes) and other eye conditions (eg, cycloplegia).
When should you not take atropine?
Who should not take ATROPINE SULFATE?
- overactive thyroid gland.
- myasthenia gravis, a skeletal muscle disorder.
- closed angle glaucoma.
- high blood pressure.
- coronary artery disease.
- chronic heart failure.
- asthma.
- a change in saliva secretion.
Can atropine be poisoned through the eye?
When considering the systemic toxicity effects of atropine as an eye drop, poisoning via the eye is likely impossible.
Are atropine eye drops contraindicated in young patients?
As there are systemic side effects of atropine eye drops, they could be contraindicated in young patients with some conditions, syndromes, and medications.
How does atropine affect the developing retina?
Acetylcholine is involved in the developing retina, and when atropine is given as an eye drop it blocks the action of acetylcholine at the muscarinic receptors which is postulated to be a mechanism by which atropine can slow eye growth and myopia progression. 4 Atropine’s ocular side effects are well known.
What is the concentration of atropine in the human body?
The atropine concentrations were 887 ng/mL in the cardiac blood, 489 ng/mL in the peripheral blood, 6693 ng/mL in the gastric contents (1.1 μg), 6753 ng/mL in the urine, and 2290 pg/mg in the hair. The blood concentrations measured in the decedent were consistent with an overdose of atropine, which was determined as the cause of death.