What is the difference between an apical vs a basolateral membrane?

The apical membrane faces the lumen and is rich in PAR and Crumbs protein complexes. The basolateral membrane contains the Scribble complex and faces the extracellular matrix.

What is apical basolateral polarity?

Epithelial cell polarity is characterized by cells with apical and basolateral membrane domains separated by adherens and tight junctions. The apical and basolateral membranes have unique protein and phospholipid compositions.

What does the basolateral membrane?

Definition. The basolateral cell membrane is the fraction of the plasma membrane at the basolateral side of the cell, which faces adjacent cells and the underlying connective tissue.

Where is basolateral membrane located?

Cellular component – Basolateral cell membrane The basolateral cell membrane is the fraction of the plasma membrane at the basolateral side of the cell, which faces adjacent cells and the underlying connective tissue.

What does the basolateral membrane do?

Vasopressin in the Kidney—Historical Aspects The presence of basolateral plasma membrane V2 receptors in the kidney and their role in water reabsorption in the principal cells of the collecting duct are well established.

What is the difference between apical and basal?

What is apical and basal? The basal side of the cell is the side that faces the basement membrane, i.e. the connective tissue layer the cell lives on. The apical side is the side that faces the opposite direction, usually towards the lumen (inside) of a tube.

What is apical basal polarity and why is it important?

Also, why is apical basal polarity important? Epithelial cells become polarized along the apical-basal axis. These include regulating the vectorial transport of ions across cell sheets during their barrier function as well as ensuring directionality during their secretory and absorptive functions.

What is apical and apical side?

The apical side is the side that faces the opposite direction, usually towards the lumen (inside) of a tube. Click to see full answer. Correspondingly, what is apical and basal surface? Epithelial cells are polarized with an apical surface facing the lumen or external environment and a basal surface facing the basement membrane.

What is a basal surface in histology?

Definition. (histology) The edge of the cell or tissue facing the underlying connective tissue. (dentistry) The impression surface of denture. Supplement. In histology, the basal surface is the bottom edge of the cell or tissue adjacent to the basement membrane.