How does a stirred-tank bioreactor work?
The core component of the stirred tank bioreactor is the agitator or impeller, which performs a wide range of functions: heat and mass transfer, aeration, and mixing for homogenization. Two types of impellers are widely used in the conventional fermentation industry: axial and radial flow impellers.
What is a bioreactor explain with diagram?
A bioreactor is a vessel in which raw materials are converted into products, using microbial plant, animal or human cells. It provides the optimal conditions by providing optimum temperature, pH, substrate, vitamins, oxygen, etc.
What is simple stirred-tank bioreactor?
A stirred-tank reactor is cylindrical in shape or having a curved base that simplifies the mixing of the reactor substances and the stirrer helps in uniform mixing and availability of oxygen throughout the bioreactor. In a sparged stirred-tank bioreactor, the sterile air is sparged through the reactor.
What is the specification of stirred-tank bioreactor?
StirCradle-Pro
| GENERAL SPECIFICATION | ||
|---|---|---|
| Features | StirCradle™-Pro 1000 | |
| Temperature | Cooling | Tap or Chilled water tank |
| Dissolved Oxygen | Range | 0 – 200 |
| Precision | Display: ±0.1 | Control: ±0.2-0.5 |
What is simple stirred-tank bioreactor 12?
A stirred-tank reactor is usually cylindrical or with a curved base to facilitate the mixing of the reactor contents and the stirrer facilitates even mixing and oxygen availability throughout the bioreactor. In sparged stirred-tank bioreactor sterile air is sparged through the reactor.
What is the difference between simple stirred and sparged stirred bioreactor?
1. There is increased surface area for oxygen transfer in the Sparged Stirred bio reactor, whereas there is less surface area as compared to Sparged tank for oxygen area in Simple Stirred bio reactors. 2. Bubbles increase the oxygen transfer area in Sparged whereas there is absence of oxygen bubbles in Simple stirred.
What is bioreactor example?
Bioreactors are vessels or tanks in which whole cells or cell-free enzymes transform raw materials into biochemical products and/or less undesirable by-products. The microbial cell itself is a miniature bioreactor; other examples include shake flasks, Petri dishes, and industrial fermentors.
What are the requirements for designing a bioreactor?
The material used for the construction of a bioreactor must have the following important properties:
- It should not be corrosive.
- It should not add any toxic substances to the fermentation media.
- It should tolerate the steam sterilization process.
- It should be able to tolerate high pressure and resist pH changes.
What is the continuous stirred tank bioreactor?
The continuous stirred tank bioreactor (CSTB) is the other suspended growth process ( Ishak et al., 2012) and is based on a conventional mixed-flow reactor (MFR) or continuous stirred tank reactor (CSTR). It requires air supply and the stirrer can be either at the top or bottom of the reactor.
What are the characteristics of a stirred tank reactor?
• A stirred tank reactor will either be approximately cylindrical or have a curved base • A curved base assists in the mixing of the reactor contents.
What is a bioreactor?
Stirred tank bioreactors consist of a cylindrical vessel with a motor driven central shaft that supports one or more agitators ( Fig. 1 ). Different kinds of agitators are used in different applications. Microbial culture vessels are generally provided with four baffles placed equidistant around the periphery of the tank.
How many impellers are there in a stirred tank bioreactor?
The number of impellers is variable and depends on the size of the bioreactor i.e., height to diameter ratio, referred to as aspect ratio. The aspect ratio of a stirred tank bioreactor is usually between 3-5. However, for animal cell culture applications, the aspect ratio is less than 2.