Is there a cure for opsoclonus?
Treatment. There are no official treatment recommendations for OMS. Management may involve: Surgery, chemotherapy , and/or radiation: When there is a tumor present, treatment such as surgery for tumor removal, chemotherapy, or radiation may be required.
What causes opsoclonus myoclonus syndrome?
Causes of OMAS OMAS may be caused by an immune reaction to a tumor called neuroblastoma or an immune reaction to a viral illness. The immune reaction causes the body to produce antibodies to the cerebellum, which is located in the back of the brain.
How common is opsoclonus myoclonus?
Opsoclonus myoclonus syndrome (OMS), also known as opsoclonus-myoclonus-ataxia (OMA), is a rare neurological disorder of unknown cause which appears to be the result of an autoimmune process involving the nervous system. It is an extremely rare condition, affecting as few as 1 in 10,000,000 people per year.
What are the symptoms of OMS?
The symptoms of OMS usually begin abruptly and can include rapid, repeated eye movements (opsoclonus or “dancing eyes”), jerking movements (myoclonus), and loss of balance (ataxia). OMS may be initially diagnosed as acute cerebellar ataxia.
What does opsoclonus look like?
Opsoclonus differs from ocular flutter in that opsoclonus changes rapidly in any direction (horizontal, vertical, torsion) — i.e. the eye movement vector is chaotic, while flutter is generally always purely horizontal. Opsoclonus may look like a a chaotic “shimmer” on direct observation.
What is opsoclonus-myoclonus syndrome in adults?
Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often with paraneoplastic etiology. It is characterized by associated ocular, motor, behavioral, sleep, and language disturbances. The onset is usually abrupt, often severe, and it can become chronic.
What is opsoclonus myoclonus ataxia syndrome?
Opsoclonus-myoclonus syndrome (OMS), also known as opsoclonus myoclonus ataxia, is a syndrome that includes opsoclonus along with diffuse or focal body myoclonus and truncal titubation with or without ataxia and other cerebellar signs.
Can Opsoclonus be intermittent?
Opsoclonus, also referred to as “saccadomania” or dancing eyes, is a rare, but striking saccade disorder, characterized by intermittent involuntary bursts of wild conjugate multidirectional back to back saccades.
What is the difference between Opsoclonus and nystagmus?
The resulting symptoms of oscillopsia and visual blurring are attributed to their large amplitude and high frequency. Opsoclonus must be differentiated from nystagmus (rapid jerks followed by a slow corrective saccade) and ocular flutter (horizontal back-to-back saccades).
What is the difference between opsoclonus and nystagmus?
What is opsoclonus-myoclonus ataxia syndrome?
What is opsoclonus-myoclonus syndrome (OMS)?
In adults, opsoclonus-myoclonus syndrome (OMS) is a rare, mostly immune-mediated movement disorder, rapidly leading to disability.
What is a synonym for opsoclonus?
Synonyms of Opsoclonus-Myoclonus Syndrome. dancing eyes-dancing feet. dancing eye syndrome (term usually used in UK) Kinsbourne syndrome. myoclonic encephalopathy, Kinsbourne type. OMAS. OMS. opsoclonic encephalopathy.
What is the prevalence of opsoclonus in children?
The peak age in children is about 18 months, with very few diagnosed before 1 year, and a long tail out to about 5 – 6 years. Occurrence of opsoclonus in infants under 6 months old is quite uncommon, and opsoclonus in that age group, when isolated, is usually from another cause. OMS occurs in only slightly more girls than boys.
What is the prognosis for children with myoclonus?
Children with the mildest symptoms have the greatest chance of returning to normal after treatment. For those with moderate severity, myoclonus tends to lessen over time, but coordination may not fully return. Some learning and behavioral issues may also remain. Those with severe symptoms have the highest risk for permanent neurological problems.