What is cholera A level biology?
cholera, an acute infection of the small intestine caused by the bacterium Vibrio cholerae and characterized by extreme diarrhea with rapid and severe depletion of body fluids and salts.
How does cholera cause diarrhea A level biology?
A bacterium called Vibrio cholerae causes cholera infection. The deadly effects of the disease are the result of a toxin the bacteria produces in the small intestine. The toxin causes the body to secrete enormous amounts of water, leading to diarrhea and a rapid loss of fluids and salts (electrolytes).
Is the organism that causes cholera prokaryotic or eukaryotic?
The bacterium as the cause of cholera was discovered by Robert Koch in 1884….
How does cholera get into cells?
Cholera toxin (CT), an AB5-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER).
Can you catch cholera from someone?
It is spread by eating or drinking food or water contaminated by the feces (poop) of an infected person. This occurs more often in underdeveloped countries lacking proper water supplies and sewage disposal. It is not likely that cholera is spread directly from one person to another.
What is cholera scientific name?
Cholera – Vibrio cholerae infection.
What category is cholera?
What is cholera? Cholera is an acute, diarrheal illness caused by infection of the intestine with the toxigenic bacterium Vibrio cholerae serogroup O1 or O139. An estimated 1.3 to 4 million people around the world get cholera each year and 21,000 to 143,000 people die from it.
Is cholera caused by a eukaryote?
As all bacteria, Vibrio cholarae is a prokaryotic organism. Prokaryotes do not have a nucleus like eukaryotes do. Their DNA is not membrane-bound, just free in the cytoplasm.
How does cholera work on a cellular level?
Once cholera toxin binds to cell surface receptors, the A Protomer can enter the cell and bind with and activate its target effector: adenylate cyclase. Increasing adenylate cyclase activity will increase cellular levels of cAMP, increasing the activity of ion pumps that remove ions from the cell.
How is an enzyme involved in cholera?
Abstract. Cholera diarrhoea is due to the action of a toxin that acts on all animal cells by stimulating the enzyme adenylate cyclase, which catalyses the production oc cyclic AMP from ATP.