What is LDS syndrome?
Overview. Loeys-Dietz syndrome (LDS) is a disorder that affects the connective tissues of the body and increases the patient’s risk of aneurysms in arteries such as the aorta. This condition is rare and was only recently identified as a condition in 2005.
What is the difference between Ehlers-Danlos syndrome and Marfan syndrome?
Differential diagnosis EDS should be distinguished from Marfan syndrome (MFS), the clinical and molecular features of which are discussed below. In EDS, the skin fragility is more prominent, and joint hypermobility is usually more severe.
What is it called when you have long fingers?
Arachnodactyly (“spider fingers”) is a medical condition which is characterized by fingers and toes that are abnormally long and slender, in comparison to the palm of the hand and arch of the foot. In some cases, the thumbs of an individual with the condition are pulled inwards towards the palm.
What gene causes Loeys-Dietz syndrome?
The five types of Loeys-Dietz syndrome are distinguished by their genetic cause: TGFBR1 gene mutations cause type I, TGFBR2 gene mutations cause type II, SMAD3 gene mutations cause type III, TGFB2 gene mutations cause type IV, and TGFB3 gene mutations cause type V.
Can people with Ehlers-Danlos syndrome donate blood?
Certain medications may delay your ability to donate blood….Medical Conditions Affecting Donation.
|Ehlers Danlos Syndrome||Acceptable|
|Ehrlichiosis||Accept if asymptomatic and treatment completed|
How do you explain EDS to someone?
Ehlers-Danlos syndrome (EDS) is a disease that weakens the connective tissues of your body. These are things like tendons and ligaments that hold parts of your body together. EDS can make your joints loose and your skin thin and easily bruised. It also can weaken blood vessels and organs.
What is hydrocephalus and what causes it?
Hydrocephalus is a central nervous system disorder characterized by excessive accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. Although this disorder is common in childhood, hydrocephalus can occur at any age and results in significant cognitive and physical handicap.
What are the signs and symptoms of hydrocephalus?
Among adults 60 years of age and older, the more common signs and symptoms of hydrocephalus are: Difficulty walking, often described as a shuffling gait or the feeling of the feet being stuck
Are abnormal osmotic gradients involved in the pathophysiology of hydrocephalus?
The pathogenesis of hydrocephalus remains unclear; however, recent reports suggest the possible involvement of abnormal osmotic gradients. Here we explore the kinetics associated with manipulating CSF osmolarity on ventricle volume (VV) in the normal rat brain.
What is the circulation theory of hydrocephalus?
Therefore, according to circulation theory, hydrocephalus is a result of a discrepancy between the amount of CSF produced and the amount of CSF absorbed. Any condition that results in the blockage of the normal flow of CSF or its absorption will result in hydrocephalus.