What is myocardial reinfarction?
Recurrent MI or reinfarction is defined as recurrence of clinical signs and symptoms of ischemia in patients with previously diagnosed MI, with accompanying electrocardiographic changes and raised serum biomarker levels consistent with myocardial necrosis .
How is reinfarction diagnosed?
The only way to confirm a diagnosis of reinfarction is to document raising titres of cardiac enzymes and second peaking of CPK MB . New fresh ST elevation after a succesful thrombolysis is also a useful sign. But ST elevation in a q lead simply reflects a wall motion defect . So it requires enzymes to confirm it.
What is infarct extension?
Infarct extension is defined clinically as early in-hospital reinfarction after a myocardial infarction. The pathologic finding of infarct extension is necrotic and healing myocardium of several different recent ages within the same vascular territory.
What is the best way to prevent reinfarction?
The clinical trials for prevention of reinfarction showed that the correction of risk factors and the use of anticoagulation and/or antiaggregation therapy, beta-blockers or Ca(++)-antagonist drugs, must be chosen in relation to the myocardial damage related to previous infarct.
What are the 3 cardiac markers?
Cardiac enzymes ― also known as cardiac biomarkers ― include myoglobin, troponin and creatine kinase.
What medication is used for myocardial infarction that reduces reinfarction and mortality?
Clopidogrel (Plavix) This agent has been shown to decrease cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome (ie, unstable angina, non-ST elevation MI [NSTEMI], or ST-elevation MI [STEMI]).
What medication is given after myocardial infarction?
Clopidogrel and ticagrelor are recommended for conservative medical management of MI in combination with aspirin (162 to 325 mg per day) for up to 12 months. Early administration of beta blockers is recommended during hospitalization after an MI.