What is sympathomimetic pharmacology?

Sympathomimetics. Sympathomimetic drugs are agents which in general mimic responses due to stimulation of sympathetic nerves. These agents are able to directly activate adrenergic receptors or to indirectly activate them by increasing norepinephrine and epinephrine (mediators of the sympathoadrenal system) levels.

What are examples of sympathomimetic drugs?

Examples

• amphetamine (Evekeo)
• benzylpiperazine (BZP)
• cathine (found in Catha edulis)
• cathinone (found in Catha edulis, khat)
• cocaine (found in Erythroxylum coca, coca)
• ephedrine (found in Ephedra)
• lisdexamfetamine (Vyvanse)
• maprotiline (Ludiomil)

What are sympatholytic drugs used for?

Abstract. Central sympatholytic drugs reduce blood pressure mainly by stimulating central α(2) -adrenergic receptors in the brainstem centers, thereby reducing sympathetic nerve activity and neuronal release of norepinephrine to the heart and peripheral circulation.

Is prazosin a sympatholytic?

It is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It can be primarily used to treat high blood pressure and post-traumatic stress disorder as a sympatholytic drug.

What is the difference between sympathomimetic and sympatholytic?

Drugs that bind to these receptors and modulate or mimic the function of the sympathetic nervous system may be divided into those which augment the system (sympathomimetics) and those which antagonize the system (sympatholytics).

What is the difference between sympathomimetic and sympatholytic drugs?

Is Ritalin a sympathomimetic?

Examples of this classification of sympathomimetics have powerful central nervous system (CNS) stimulant actions, which explains their use in the management of ADHD and narcolepsy but also have some peripheral α and β actions. Examples include Ritalin (methylphenidate) and Focalin (dexmethylphenidate).

Is clonidine a sympatholytic?

Abrupt cessation of clonidine is known to precipitate symptoms of sympathetic overactivity, such as anxiety, tremor, headache, palpitation, and rebound hypertension within 36 to 72 hours of discontinuation. 15,16 A rise in BP above pretreatment values is less common.