What is the substitute for benzathine penicillin?

What is the substitute for benzathine penicillin?

Azithromycin may be a viable alternative to benzathine penicillin G for syphilis treatment.

What is an alternative to penicillin G?

menigitidis and other penicillin-susceptible pathogens, ampicillin, many cephalosporins or vancomycin, clindamycin, erythromycin or other macrolides may provide adequate substitutes for aqueous penicillin G, depending on the pathogen.

Is Penicillin G benzathine water soluble?

Penicillin G is soluble in water, attains high concentrations in blood, and is excreted in urine in 4 to 6 hours. Penicillin G is available in crystalline, procaine, and benzathine forms. Because it is unstable at low pH, oral administration is not possible, so the agent is administered by injection.

What is the most appropriate way to administer penicillin G?

Penicillin G procaine (aqueous) is for intramuscular injection only. Administer by DEEP INTRAMUSCULAR INJECTION in the upper, outer quadrant of the buttock (dorsogluteal) or the ventrogluteal site. In neonates, infants and small children, the midlateral aspect of the thigh may be preferable.

Is there an over the counter substitute for penicillin?

Can you buy over-the-counter (OTC) penicillin? No. Penicillin requires a prescription from a medical professional. Some topical antibiotics used to treat minor cuts, scrapes, and burns are available over the counter.

What is alternative of ceftriaxone?

Current treatment is with ceftriaxone, but there is increasing evidence of antimicrobial resistance reducing its effectiveness. Gentamicin is a potential alternative treatment requiring further evaluation.

What is the difference between penicillin G benzathine and procaine?

Benzathine is the least soluble salt form of penicillin G, thus providing the longest duration of action (up to 3 weeks). Penicillin G procaine is usually given once daily and injected into the midlateral thigh or upper outer quadrant of the gluteus maximus.

How do you dilute benzathine penicillin?

Reconstitution of the suspension for intramuscular injection: The suspension must be prepared aseptically. The contents of the vial should be reconstituted in at least 2ml (0.6 Million I.U.), 3.5ml (1.2 Million I.U.), or 5ml (2.4 Million I.U.) of diluent (e.g. water for injections which is included in the pack).

How is penicillin G benzathine administered?

Long-acting penicillin G benzathine (Bicillin® L-A) is the preferred antibiotic treatment for syphilis. Each dose requires two intramuscular injections, one injection into each hip or buttock muscle at the same visit. One dose of Bicillin® L-A 2.4 million units is usually adequate to treat early syphilis.

How do you administer benzathine penicillin?

How should this medicine be used? Penicillin G benzathine injection comes as a suspension (liquid) in a prefilled syringe to inject into the muscles of the buttocks or thigh by a doctor or nurse in a medical facility. Penicillin G benzathine injection may be given as a single dose.

How do you make natural penicillin?

How did they make penicillin?

  1. Penicillium mold naturally produces the antibiotic penicillin.
  2. Scientists learned to grow Penicillium mold in deep fermentation tanks by adding a kind of sugar and other ingredients.
  3. Then, scientists separated the penicillin product from the mold.