What is Tropolone made of?
Tropones and tropolones are an important class of seven-membered non-benzenoid aromatic compounds. They can be prepared directly by oxidation of seven-membered rings. They can also be derived from cyclization or cycloaddition of appropriate precursors followed by elimination or rearrangement.
Which plant contains alkaloids with tropolone ring?
The colchicine site is named from the well-known tropolone alkaloid isolated from Colchicum autumnale, a plant widely employed in traditional medicine and still used in the treatment of gout.
What is the structure of Tropolone?
C₇H₆O₂Tropolone / Formula
What is Tropolone used for?
Tropolone is a bactericidal antibiotic composed of a seven-membered aromatic ring. It targets a wide variety of gram-positive and gram-negative bacteria. Tropolone has been used to prepared fused heterocycles and Ga(III) and In(III) complexes. It is also a reagent used to reduce sugars.
What type of compound is Tropolone?
Tropolone is a cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii. It has a role as a bacterial metabolite, a toxin and a fungicide. It is a cyclic ketone, an enol and an alpha-hydroxy ketone.
Is Tropolone benzenoid aromatic compounds?
Tropolone derivatives are also classiﬁed as non-benzenoid aromatic compounds.
What are tropane alkaloids?
Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs Secondary metabolites of Solanaceae plants, sharing tropane skeleton as a common structural feature, are sharply divided into two classes: tropine and ecgonine derivatives.
What is tropolone I?
THE existence of a new type of aromatic ring system, tropolone (I), was first postulated 1 to account for the chemistry of stipitatic acid, and the occurrence of this ring system in a variety of natural products has now been established 2.
How many naturally occurring tropolone derivatives are there?
Around 200 naturally occurring tropolone derivatives have been isolated, mostly from plants and fungi.
Can we predict the behaviour of tropolone?
Various derivatives of tropolone have been synthesized 3, and recently three independent syntheses of tropolone have been described 4. Since it is evident that its chemistry will soon be investigated in detail, it seems of interest to see whether its behaviour can be predicted theoretically before such experimental evidence is at hand.