What is tumor morphology?
The morphology of a cancer refers to the histological classification of the cancer tissue (histopathological type) and a description of the course of development that a tumour is likely to take: benign or malignant (behaviour).
What is the arrangement of a cancer cell?
The nucleus appears both larger and darker than normal cells. The reason for the darkness is that the nucleus of cancer cells contains excess DNA. Up close, cancer cells often have an abnormal number of chromosomes that are arranged in a disorganized fashion.
How do you describe cancer cell morphology?
Morphologically, the cancerous cell is characterized by a large nucleus, having an irregular size and shape, the nucleoli are prominent, the cytoplasm is scarce and intensely colored or, on the contrary, is pale.
What is the structure of a tumor?
Solid tumors have a distinct structure that mimics that of normal tissues and comprises two distinct but interdependent compartments: the parenchyma (neoplastic cells) and the stroma that the neoplastic cells induce and in which they are dispersed.
How do you code morphology?
There are three parts to a complete morphology code: 4 digits cell type (histology) 1 digit behavior. 1 digit grade, differentiation or phenotype….Behavior.
| Code | Neoplasm |
|---|---|
| /3 | Malignant, primary site |
| /6* | Malignant, metastatic site |
| Malignant, secondary site | |
| /9* | Malignant, uncertain whether primary or metastatic site |
What Anaplasia means?
(A-nuh-PLAS-tik) A term used to describe cancer cells that divide rapidly and have little or no resemblance to normal cells.
What is the relationship between the cell cycle and cancer?
Superficially, the connection between the cell cycle and cancer is obvious: cell cycle machinery controls cell proliferation, and cancer is a disease of inappropriate cell proliferation. Fundamentally, all cancers permit the existence of too many cells.
How do cancer cells follow the cell cycle?
Cancer is unchecked cell growth. Mutations in genes can cause cancer by accelerating cell division rates or inhibiting normal controls on the system, such as cell cycle arrest or programmed cell death. As a mass of cancerous cells grows, it can develop into a tumor.
What are the 7 hallmarks of cancer?
We define seven hallmarks of cancer: selective growth and proliferative advantage, altered stress response favoring overall survival, vascularization, invasion and metastasis, metabolic rewiring, an abetting microenvironment, and immune modulation, while highlighting some considerations for the future of the field.
What is a tumor pathophysiology?
This includes cause of the disease, diagnosis, how the disease develops (pathogenesis), mechanism and natural course of the disease. They also deal with biochemical features, progression, and prognosis or outcome of the disease.
What are the characteristics of tumors?
tumour, also spelled tumor, also called neoplasm, a mass of abnormal tissue that arises without obvious cause from preexisting body cells, has no purposeful function, and is characterized by a tendency to independent and unrestrained growth.