What plastic is solvent resistant?
Polyolefins for good chemical resistance The two most common polyolefin materials that are used for applications involving chemical environments are polyethylene (HDPE) and polypropylene (PP). Polyethylene and polypropylene: Have good chemical resistance at room temperature.
Is Ultem brittle?
While Ultem® is also resistant to a broad spectrum of chemicals, its brittle nature makes it more prone to environmental stress cracking.
Can you injection mold Ultem?
This premium quality plastic material is resistant to hot water and steam and can withstand repeated cycles in a steam autoclave. Ultem™ molding is a less expensive alternative to high-end PEEK plastic material. Ultem™ is a highly-effective injection molding plastic.
Can Ultem be glued?
Bonding Ultem to dissimilar materials is a particular problem due to it’s high thermal expansion coefficient–six times that of steel (unfilled PEI). As a consequence the adhesive bond joint must be designed to accommodate the expansion/contraction differential between materials to avoid bond failure.
Does hydrogen peroxide dissolve plastic?
H2O2 is a strong oxidizer. I wouldn’t even dare try it on anything metal. On plastic, it would perfectly be fine as long as it’s not the industrial 35% grade.
What is the most chemical resistant material?
1. PTFE (or Teflon™) – PTFE, also commonly known as Teflon™, is one of the most acid resistant materials available and is commonly used in chemical and pharmaceutical lab applications.
Can you machine Ultem?
There’s more than one particular type of ULTEM PEI you can machine, and each has slightly different properties for perfecting this material’s use in different applications.
What is Ultem material?
ULTEM is an amorphous thermoplastic polyetherimide (PEI) material that combines exceptional mechanical, thermal, and electrical properties. Natural ULTEM® 1000 (unreinforced) is a translucent amber material.
What is Ultem resin?
ULTEM® Polyetherimide resin, PEI, is an amorphous high performance polymer which is characterized by excellent thermal properties, good chemical resistance, inherent flame retardancy and exceptional dimensional stability.
Why is dish soap used in elephant toothpaste?
The oxygen gas forms bubbles. These bubbles would usually escape from the liquid and pop quickly. But adding a little dish soap provides additional surface tension, allowing the bubbles to get trapped and creating lots of foam. This foam looks like a giant squeeze of toothpaste—almost big enough for an elephant!
Is hydrogen peroxide stable in water?
It is miscible with cold water and is soluble in alcohol and ether. Although pure hydrogen peroxide is fairly stable, it decomposes into water and oxygen when heated above about 80°C; it also decomposes in the presence of numerous catalysts, e.g., most metals, acids, or oxidizable organic materials.
What are the possible side effects of mek1/mek2 inhibitors?
In some studies on mice, intermittent dosing was associated with improved survival, and perhaps less toxicity. MEK1/MEK2 inhibitors have a tendency to cause a papulopustular rash, seen in 57% of patients. Other side effects include diarrhea in 43%, whereas peripheral edema is observed in 26%.
How do MEK inhibitors work?
MEK inhibitors bind to and inhibit MEK, inhibiting MEK-dependent cell signaling. This inhibition leads to cell death and the inhibition of tumor growth. These are allosteric binding inhibitors of MEK which inhibit either MEK1 alone, or both MEK1 and MEK2.
What is Mekmek?
MEK is a downstream protein kinase which can be targeted to prevent reactivation of the MAPK pathway in the presence of BRAF or RAS mutations. Normally, ERK1/2 activation initiates a variety of cellular and nuclear pathways, while also inhibiting Raf activity by a feedback loop to modulate the activity of the MAPK pathway.
Are MEK inhibitors effective against BRAF-mutant non-small cell lung carcinoma?
BRAF inhibition with an MEK1/2 inhibitor has also been approved for the therapy of advanced BRAF-mutant non-small cell lung carcinoma. Other MEK inhibitors are currently undergoing preclinical and clinical trials for various cancers in which MAPK/ERK is overactive especially BRAF-mutated melanomas and KRAS/BRAF mutated colorectal cancer.